ASSC8 abstract



The medial motor areas and voluntary action

Matthew FS Rushworth
University of Oxford - UK

Disruption of the medial motor areas with TMS impairs movements when the movements are chosen by the subjects themselves but not when they are cued by external instructions. The medial motor areas may be critical for the production of voluntary or "willed" actions. Lesion and fMRI data suggest that other brain regions are more concerned with selecting movements when the movements are cued by external instructions. Some medial motor areas have strong connections with the limbic system which processes information related to reinforcement and motivation. These connexions may underlie the medial motor areas involvement in the selection of willed actions. When subjects are freely choosing between different possible actions they may be choosing an action on the basis of the consequence it is anticipated it will have for reinforcement and motivation. The medial motor areas select which action to make on the basis of reinforcement associations and they decide whether it is worth making any action at all.